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excitatory amino acid reuptake inhibitor : ウィキペディア英語版
excitatory amino acid reuptake inhibitor
An excitatory amino acid reuptake inhibitor (EAARI) is a type of drug which inhibits the reuptake of the excitatory neurotransmitters glutamate and aspartate by blocking one or more of the excitatory amino acid transporters (EAATs). Examples of EAARIs include dihydrokainic acid (DHK) and WAY-213,613, selective blockers of EAAT2 (GLT-1), and L-''trans''-2,4-PDC, a non-selective blocker of all five EAATs. Amphetamine is a selective noncompetitive reuptake inhibitor of presynaptic EAAT3 (via transporter endocytosis) in dopamine neurons. L-Theanine is reported to inhibit glutamate reuptake via direct blockade of glutamate transporters as well.
==See also==

* Reuptake inhibitor
* Glutamatergic
* GABA reuptake inhibitor
* Glycine reuptake inhibitor
* Excitatory amino acid receptor agonist
* Excitatory amino acid receptor antagonist

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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